Complete Guide to CBD E-Liquids for 2022

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Complete Guide to CBD E-Liquids for 2022

CBD E-Liquids are a popular way to consume cannabidiol. While people take CBD in many forms, like CBD gummies, CBD oral drops, and CBD supplements, CBD vapes are an excellent way to unlock hemp extract’s myriad health and well-being possibilities. This guide will go deep into what CBD E-Liquids are, what they can do for you, how they’re made, and why they’re so popular. 
ice mint CBD e-liquids bottle

What are CBD E-Liquids?

CBD — short for cannabidiol — is a chemical found in hemp and cannabis plants. CBD is a phytocannabinoid, i.e., compounds produced in cannabis plants that deliver a variety of active effects.

The cannabis plant contains more than 100 other cannabinoids. The most famous of these is THC, which is the substance that causes the euphoric effects found in marijuana.

CBD products either don’t have any THC, or they contain less than 0.3% (per UK law). As a result, they don’t have any psychoactive effects. In other words, they won’t get you high.

In the 1940s, a chemist by the name of Robert Adams isolated CBD from the hemp plant. Over the next few decades, other researchers contributed to Adams’ work.

More recently, things really began to take off as CBD products started to appear on the UK high street.

While CBD oils were the first major step, CBD coffee, supplements, edibles, and other products soon became available.

However, one of the most intriguing applications of CBD was CBD vapes. Instead of taking CBD orally through drops or sweets, consumers could vape CBD to access its health benefits quickly.

CBD E-Liquids, also known as CBD vape juice, are liquids that users can consume via e-cigarettes. Just like other vaping devices, a battery heats up a coil, which vapourises the liquid.

Once the user draws the CBD E-Liquid vapour into their lungs, it is taken into the bloodstream via the blood vessels in the lungs. From there, the CBD can do its work.

For a deep dive into how CBD affects our body, read our article below.

RELATED: How Does CBD Work?

CBD E-Liquids: Full-Spectrum, Broad-Spectrum, or Isolate?

CBD E-Liquid come in a variety of forms. They are either:

  • Full-spectrum CBD
  • Broad-spectrum CBD
  • Isolate CBD

The difference between these different formats is about the exclusion or inclusion of certain parts of the hemp plant.

Full-Spectrum CBD

Full-spectrum CBD contains all contents of the hemp plant, including tiny amounts (0.3%) of THC. Some of its compounds are other cannabinoids, terpenes, essential oils, flavonoids, minerals, and plant esters.

RELATED: CBD Terpenes: What Are They & How Do They Work?

Broad-Spectrum CBD

Broad-spectrum CBD is similar to full-spectrum in that it contains lots of different cannabinoids and components of the cannabis plant. However, it contains zero THC. 

Isolate CBD

Isolate CBD, as the name suggests, is CBD that has been isolated from the hemp plant. It’s the purest form of CBD and doesn’t contain any other compounds of the cannabis plant, including THC, essential oils, flavonoids, or terpenes.

These different production methods are designed to meet a variety of needs. CBD isolate or broad-spectrum CBD’s lack of THC will appeal to certain people. 

Some studies suggest that to unlock the full effects of CBD, full-spectrum is required

However, this is open to debate, and users report health and well-being benefits from all three. For a deeper dive into the different types of CBD, click the link below.

RELATED: ​​Full-Spectrum CBD vs Isolate CBD

woman vaping CBD e-liquids

What do CBD E-Liquids contain?

Some people will already be familiar with CBD oils. They were some of the first CBD products that appeared on these shores. However, it’s important to distinguish the differences between CBD oils and CBD E-Liquids.

CBD oils are made from CBD and a carrier oil, like coconut. They may also contain other terpenes (which give it a hemp taste and smell) or other flavourings. The liquid is quite thick, and these oils should be taken as drops under the tongue.

CBD E-Liquids are a distinctly different thing. While they do contain CBD, they are also made with:

  • Propylene Glycol (PG)
  • Vegetable Glycerine (VG)
  • Distilled water
  • MHRA-approved Flavourings

Generally, CBD E-Liquid manufacturers use thinners to keep the product watery. They need to be thin so that users can use them in CBD vapes.

vitality CBD e-liquids bottle

What are the effects of vaping CBD E-Liquids?

Like we said, CBD won’t get you high. 

However, users report several pleasure effects from vaping CBD E-Liquids, such as:

  • Pain reduction
  • Elevated mood
  • Relaxation
  • Reduced anxiety
  • Reduced stress

Vaping CBD has some drawbacks compared to other methods. For starters, it doesn’t last as long, with the effects wearing off after an hour or two.

So, if they want an all-day effect, people need to carry their CBD vapes about.

Is Vaping CBD E-Liquids Efficient?

One interesting point to note is how CBD E-Liquids are delivered to the body. By vaping CBD juice, users can feel the effects quite quickly. The reason is that it is absorbed through the lungs and straight into the bloodstream. 

Other methods of taking CBD, like edibles and supplements, can take longer to work because they need to be broken down by the digestive system. CBD E-Liquids bypass this process and work swiftly.

So, let’s look at the bioavailability of a few of the different CBD formats.

Bioavailability of different CBD products

There are lots of ways to take CBD. However, some are more efficient than others. The mechanism that explains all of this is bioavailability.

Simply, bioavailability measures how much and how quickly a substance is absorbed into the bloodstream. Once CBD is in the blood, it can move into tissues and cells.

Understanding the bioavailability of each format is useful. It can help users:

  • Consume the right dose
  • Understand how long the effects will laugh
  • Make cost-effective CBD purchases

To understand how CBD products stack up against each other, well look at four different ways you can consume this substance:

  • Oral – i.e., eating gummies or taking supplements
  • Sublingual – i.e., putting oil under your tongue
  • Vaping – i.e., using CBD vapes
  • Topical – i.e. applying CBD cream


Oral consumption of CBD is a popular method. It doesn’t require any special equipment and it’s easy to do. Oral CBD comes in a lot of different forms, like edibles, supplements, gummies, sweets, and even CBD drinks.

A lot of people don’t like the taste of CBD. You can mask the taste of oral products by mixing them with other products. However, because it enters the bloodstream through the digestive system, the effects can take longer to kick in—but they last longer.

Bioavailability of Oral CBD: 4 to 20%

Time to take effect: Up to 2hrs

Duration: Around 4hrs


Taking CBD sublingually—i.e. under the tongue—is another popular method. It’s easy: most people do it by dropping oil under the tongue. The oil is then broken down by enzymes in the mouth, bypassing the digestive system.

Bioavailability of Sublingual CBD: 15 to 30%

Time to take effect: 15-20 mins

Duration: 1-10 hrs, depending on the dose


Vaping CBD E-Liquids is popular because of their near-instantaneous effects. The reason for the quick absorption is that CBD vapes heat the substance.

The downside is that the effects don’t last as long. However, it’s not hard to top up, which is why CBD vapes are one of the best and most efficient delivery systems.

Bioavailability of Oral CBD: 35 to 45%

Time to take effect: A few minutes

Duration: 1-2 hrs


You can take CBD topically by rubbing CBD lotions or creams onto your skin. While it’s not the most efficient way to absorb CBD, users report that it can work on specific areas, like muscles or joints. As a result, people tend to target pain by rubbing the cream into specific areas.

Bioavailability of Oral CBD: 5-10%

Time to take effect: 20-30 mins

Duration: Up to 6hrs

NOTE: It’s important to note that the numbers above are just a rough guideline. I’ve seen people on forums and social media report numbers that are all over the map. Things like body weight, body composition, and varying metabolic rates mean that everyone absorbs CBD in different ways. 

What size dose you take matters too. For example, large doses take longer to have an effect. Interestingly, one study suggests that mid-sized doses were better for reducing anxiety than smaller or larger amounts.


How to vape CBD

Vaping CBD E-Liquids is a fairly easy process. All you need are:

  • A vaping device
  • Some CBD E-Liquids

There are two ways that you can do this:

  • Fill a tank or pod with a bottle of CBD E-Liquid
  • Use a pre-filled CBD E-Liquid cartridge and screw it onto a compatible device

If you’ve vaped nicotine E-Liquids before, the process will be very familiar.

But if you’re not, here is a simple step-by-step guide to vaping CBD E-Liquids with a vape device.

#1. If your tank or pod has replaceable coils, prime them with your CBD juice. 

#2. Fill your tank or pod with your CBD E-Liquid

#3. Allow it to sit for at least 10 minutes to let the coil absorb the juice

#4. Inhale, but start with small drags

#5. Wait for 5 to 10 minutes to notice the effect—always start slow and build up the dose gradually.

However, if all that seems like too much work for you, CBD E-Liquid cartridges are the way the go. Carts are pre-filled tanks that you can easily screw onto a rechargeable device, like the Diamond Mist Ego 510 CBD cartridge Battery. 

You don’t have to prime to coil or wait for your CBD E-Liquids to be absorbed. But the same principles apply to taking small, incremental doses.

RELATED: How to Use a CBD Cartridge: 3 Easy Steps to CBD Vaping

Do CBD vapes contain nicotine?

CBD E-Liquids don’t — and should never — contain nicotine. While you can use CBD and nicotine juices in similar devices, mixing the juices is a bad idea because nicotine actually degrades CBD.

CBD e-liquids cartridge

What vape kits are best for CBD E-Liquids?

Typically, CBD E-Liquids come with VG/PG ratios of:

  • 50/50
  • 35/65
  • 25/75

Ultimately, what that means is that CBD juice is on the thinner end of the scale.

Sub-ohm or direct-to-lung (DTL) devices are designed with higher VG content in mind. As a result, they work best with more viscous liquids. Using CBD E-Liquid in these devices can result in leaking, which you definitely don’t want.

Mouth-to-lung (MTL) kits are your best choice for CBD E-Liquids. They are built to handle juice as high as 100% PG. 

MTL kits are generally less powerful than DTL kits. However, that’s not a disadvantage when it comes to CBD E-Liquids, because they don’t need to be vaped at a high wattage.

Best Wattage for CBD Vapes

You don’t need a high-powered device to vape CBD E-Liquids. In fact, you need to be careful to keep the wattage low.

The best wattage settings for CBD vapes are between 10 – 30W. Anything higher than this can result in a burnt taste. More importantly, it can also destroy the CBD compounds.

I prefer settings below 20W for CBD. There is a considerable amount of debate about this in the CBD vaping community, but I don’t see the advantage of ramping up past 20W.

Whatever your wattage preference, it’s best to start out at the lowest setting and gradually cycle up until you hit your sweet spot.

Best coils for CBD vapes

The best coils for CBD E-Liquids are 1.0-ohm and above. Again, this is because most CBD juice is either mostly PG or a 50/50 blend with VG.

So, use coils that are designed for high PG E-Liquids and lower-wattage devices. 

CBD e-liquids and other bottles


CBD E-Liquids are an efficient and easy way to consume CBD. Unlike other methods, like oral, sublingual, or topical application of creams, CBD vapes are absorbed quickly into your bloodstream. This process makes them popular with users who are looking for quick relief from a variety of symptoms.

It’s best to vape CBD juice in low-powered devices with 1.0-ohm or above coils. If you have a nicotine E-Liquid device already, you can use that. However, makes sure not to mix your juice with nicotine if you want to get the full effect of CBD.

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